25 اردیبهشت 1403
باقر افتخاري سيس

باقر افتخاری سیس

مرتبه علمی: استاد
نشانی: مراغه، گلشهر دانشگاه مراغه، دانشکده علوم پایه، گروه شیمی
تحصیلات: دکترای تخصصی / شیمی آلی
تلفن: +984137278900-Int.512
دانشکده: دانشکده علوم پایه

مشخصات پژوهش

عنوان
Halloysite-based hybrid bionanocomposite hydrogels as potential drug delivery systems
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Oxidized starch, Chitosan, Halloysite, Drug delivery systems
سال
2017
مجله APPLIED CLAY SCIENCE
شناسه DOI 10.1016/j.clay.2017.08.009
پژوهشگران نوشین صباغ ، علی اکبری ، ناصر ارسلانی ، باقر افتخاری سیس ، حامد همیشه کار

چکیده

In this investigation, the preparation of novel Halloysite-based chitosan/oxidized starch (Hal/CTS/OSR) Hybrid bionanocomposite hydrogels is described. The obtained hybrid hydrogels were characterized by using FT-IR, SEM, XRD, TGA and DTG techniques. In addition, the efficiency of hydrogels as drug delivery systems was studied. The results demonstrated that depending on experimental parameters, such as the ratio of CTS/OSR, and the type of Hal nanotubes (modified or unmodified), the hydrogel properties can be affected and modulated significantly. 74.3%, 71.2% and 69.45% MTZ release were observed for CTS/OSR/mHal 10, CTS/OSR and CTS/OSR/Hal 10 respectively.