May 19, 2024
Bagher Eftekhari-Sis

Bagher Eftekhari-Sis

Academic rank: Professor
Address: Department of Chemistry, University of Maragheh, P.O.Box 55181-83111, Maragheh, Iran
Education: PhD. in Organic Chemistry
Phone: +984137278900-Int.512
Faculty: Faculty of Basic Sciences

Research

Title
Halloysite-based hybrid bionanocomposite hydrogels as potential drug delivery systems
Type Article
Keywords
Oxidized starch, Chitosan, Halloysite, Drug delivery systems
Year
2017
Journal APPLIED CLAY SCIENCE
DOI 10.1016/j.clay.2017.08.009
Researchers Nooshin Sabbagh، ، ، Bagher Eftekhari-Sis، Hamed Hamishehkar

Abstract

In this investigation, the preparation of novel Halloysite-based chitosan/oxidized starch (Hal/CTS/OSR) Hybrid bionanocomposite hydrogels is described. The obtained hybrid hydrogels were characterized by using FT-IR, SEM, XRD, TGA and DTG techniques. In addition, the efficiency of hydrogels as drug delivery systems was studied. The results demonstrated that depending on experimental parameters, such as the ratio of CTS/OSR, and the type of Hal nanotubes (modified or unmodified), the hydrogel properties can be affected and modulated significantly. 74.3%, 71.2% and 69.45% MTZ release were observed for CTS/OSR/mHal 10, CTS/OSR and CTS/OSR/Hal 10 respectively.