Abstract Background and Objectives Job satisfaction is one of the most basic components of mental health, dynamism, efficiency, and creativity of employees in any job or profession. The present study aimed to determine the relationship between self-efficacy, self-regulation, locus of control, and job satisfaction in rotating shift employees of Imam Khomeini Hospital in Urmia. Methods The research method is correlational. The statistical population in this study included all male employees working on rotating shifts in Imam Khomeini Hospital in Urmia, from which 150 people were selected as a sample based on the stratified random sampling method. This study used the Hoffman and Kashdan Emotional Self-Regulation Questionnaire, the Scherrer Self-Efficacy Questionnaire, the Rutter Locus of Control Test, and the Smith, Kendall, and Hewlett Job Satisfaction Questionnaire as data collection tools. Pearson correlation analysis and multiple regression analysis with SPSS25 were used to analyze the hypotheses. Results The study showed a relationship between self-efficacy and job satisfaction (0.001). There is also a positive relationship between self-regulation and job satisfaction and locus of control with job satisfaction (0.001). In the components of emotional self-regulation, the relationship of all three elements of concealment, compromise, and tolerance with job satisfaction was confirmed (0.001). Conclusion In short, self-efficacy, self-regulation, and internal locus of control are three important factors in determining the level of job satisfaction of employees. Cultivating these characteristics in people can help increase job satisfaction and, as a result, improve the performance and productivity of organizations.
