Nanoencapsulation of an acaricide, clofentezine, was investigated through a simple and green route using polyethylene glycol (PEG). In comparison to conventional formulations of clofentezine, clofentezine nanocapsules (Clo@NPs) showed improved persistence and solubility. TEM showed spherical nanoparticles that were 230 ± 20 nm. The LC50 values for clofentezine and Clo@NPs against adults were 297.65 and 88.44 µg a.i./mL, respectively. Controlled release experiments showed that Clo@NPs releases the active ingredient over a prolonged period. The results showed that the acaricidal efficacy of nanoformulated clofentzine was improved. The nanoparticle formulation will be more economical and environment friendly to apply compared to traditional formulations.
