In this paper, different combined cooling, heating and power (CCHP) systems are introduced and studied for waste heat recovery from a cement plant located in Şanliurfa, Turkey considering domestic applications. One of the systems is based on the steam Rankine cycle and the next is based on recuperative organic Rankine cycle (ORC), while both of them are equipped with a LiBr–H2O absorption chiller to produce cooling. Different working fluids are considered in the ORC simulation. Energy, exergy and exergoeconomic principles are applied to compare the examined systems from thermodynamic, sustainability and economic aspects. It is observed that utilizing siloxanes as the working fluid leads to efficient performance of the ORC. Besides, employed heat recovery steam generator in the Rankine cycle and evaporator in the ORC found to be the most exergy destructive components. Results revealed that the CCHP system operating with ORC (MM as working fluid) has a better performance thermodynamically with energy utilization factor, exergy efficiency and sustainability index of 98.07, 63.6% and 2.747, respectively. This is while, Rankine-based CCHP is economically preferable with a payback period of 4.738 year compared to the system operating with ORC and a payback period of 5.074 year.