his experiment aimed to evaluate the effect of different herbicides, including H0: no application of herbicide, H1: trifluralin as a pre-emergence herbicide, H2: cycloxydim, H3: haloxyfop-R-methyl, and H4: pinoxaden as post-emergence herbicides, on weed growth and camelina performance characteristics under well-irrigated (I1) and rainfed (I2) conditions. The response of the studied traits to herbicides varied across moisture regimes. The lowest population density was recorded under conditions of I1H2 (8 plant m-2), I2H3(7 plant m-2), and I2H4 (6.33 plant m-2). The lowest weed biomass was obtained under rainfed conditions with the use of cycloxydim. The tallest plants were recorded under I1H2 conditions (110.96 cm), and the shortest plants were recorded under I2H0 conditions (51.87 cm). The highest amount of chlorophyll was observed in plants grown under the conditions of I1H4 (58.83 SPAD unit), I1H2(56.70), and the lowest amount under the conditions of I2H0 (36.33) and I2H1 (39.00). Seed yield under rainfed conditions decreased by 33% compared to well-irrigated conditions. The highest seed yield was obtained by using cycloxydim (1135 kg ha-1) and pinoxaden (1110 kg ha-1). Although weed populations were low under rainfed conditions, the effectiveness of herbicides was more prominent under fully irrigated conditions than under rainfed conditions.