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Maryam Moosavifar

Maryam Moosavifar

Academic rank: Associate Professor
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Education: PhD.
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Research

Title
Biocompatibility assessment of graphene oxide-hydroxyapatite coating applied on TiO2nanotubes by ultrasound-assisted pulse electrodeposition
Type
JournalPaper
Keywords
Hydroxyapatite Graphene oxide Ultrasound-assisted electrodeposition Biocompatibility Simulated bodyflui
Year
2018
Journal Materials Science & Engineering C-Materials for Biological Applications
DOI
Researchers ، jafar khalil-allafi ، seyed omid reza sheykholeslami ، Maryam Moosavifar

Abstract

In this study, the ultrasound-assisted pulse electrodeposition was introduced to fabricate the graphene oxide (GO)-hydroxyapatite (HA) coating on TiO2 nanotubes. The results of the X-ray diffraction (XRD), Fourier Transform Infrared spectroscope (FTIR), Transmission Electron Microscope (TEM) and micro-Raman spectroscopy showed the successful synthesis of GO. The Scanning Electron Microscope (SEM) images revealed that in the presence of ultrasonic waves and GO sheets a more compact HA-based coating with refined microstructure could be formed on the pretreated titanium. The results of micro-Raman analysis confirmed the successful incorporation of the reinforcement filler of GO into the coating electrodeposited by the ultrasound-assisted method. The FTIR analysis showed that the GO-HA coating was consisted predominantly of the B-type carbonated HA (CHA) phase. The pretreatment of the substrate and incorporation of the GO sheets into the HA coating had a significant effect on improving the bonding strength at the coating–substrate interface. Moreover, the results of the fibroblast cell culture and 3‑(4,5‑dimethylthiazolyl‑2)‑2, 5‑diphenyltetrazolium bromide (MTT) assay after 2 days demonstrated a higher percentage of cell activity for the GO-HA coated sample. Finally, the 7-day exposure to simulated bodyfluid (SBF) showed a faster rate of apatite precipitation on the GO-HA coating, as compared to the HA coating and pretreated titanium