Diabetes is a widespread endocrine disease that causes high blood glucose (blood sugar) levels due to defects in insulin secretion, function, or both. Daily blood glucose monitoring is important for managing diabetes, as elevated blood glucose levels can cause severe adverse health effects. This paper reviews chemiluminescence (CL)-based analytical methods for glucose determination in real samples, including food and body fluids. It discusses and compares, in some cases, various aspects of research directed to improve the analytical perfor- mance of CL methods for glucose measurement. It covers the principles of enzyme-based CL methods and the non-enzymatic CL methods, the mechanism and catalysts of CL reactions, and various instrumental configura- tions, among others. The surveyed publications go from the earliest—published in 1974, as far as the author knows—to the most recent.
