Nowadays, giant organic molecules have taken a great attention in nanoarchitecturing of silica materials. Silica nanostructure binded dendrimers play a crucial role in the nextgeneration technologies within many fields such as medicine, drug delivery, sensors, catalysis, water treatment, etc. This paper discusses silica nanostructures which are arrayed by dendrimers and have been used for many applications such as drug delivery and catalysis. Also, this paper elaborates some possible pathways of binding a dendrimer to a silica surface. Synthesis of dendrimers on the surface of silica nanostructure is also discussed.