Emerging antibiotic resistant bacteria as a severe health care concern, threatens the humans worldwide. Developing new effective alternatives to antibiotics is critical in therapeutic approaches. Bacteriophages as natural antibacterial agents can play significant role to control antibiotic-resistant bacterial infections. This assay provides an overview of phage therapy today, its outcome in the future and the way of using unique characteristics and potential of phages in phage therapy. Also, it leads to address the challenging barriers preventing of clinical settings to use the phages in therapeutic purposes. In spite of clinical potential of phages, some challenges in the field of biology, safety, economy and… should be investigated to further implementation and acceptance of phages in treatment of bacterial infections.
