The reinforcement of various materials by nanofillers as nanocomposites has recently received the attention of many researchers. In the present research, molecular dynamics simulations are used to investigate the influence of nanowire (NW)/carbon nanotube (CNT) reinforcement on the buckling behavior of metallic glass matrix nanocomposites (MGMNCs). The buckling characteristics of nanocomposites made by adding Cu NWs, CNTs and Cu NW-encapsulated CNTs to metallic glass matrices are studied. The results demonstrate thatMGalloys comprising just two elements (Cu and Zr) with higher Cu percentage have higher mechanical stability. Also, it is observed that addingNW leads to a negative effect on the buckling behavior, while addingCNTand NW-encapsulatedCNT considerably increases the buckling force and strain of the metallic glass models. Moreover, it is found that the filledCNTis the most effective nanofiller for amending the buckling behavior of metallic glasses. Furthermore, as the size of nanofillers gets larger, the critical force increases and the critical strain decreases