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Title
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New route to 1,4-oxazepane and 1,4-diazepane derivatives: synthesis from N -propargylamines
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Type
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JournalPaper
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Keywords
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diazepane; -propargylamine
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Abstract
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N-Propargylamines are one of the most useful and versatile building blocks in organic synthesis that are successfully transformed into many significant N-heterocycles. Due to high atom economy and shorter synthetic routes, the synthesis of 1,4-oxazepane and 1,4-diazepane cores from N-propargylamines have undergone an explosive growth in recent years. This review gives an overview of new developments in the synthesis of the title compounds from N-propargylamines in recent years. Mechanistic aspects of the reactions are considered and discussed in detail.
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Researchers
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Mehdi D. Esrafili (Fifth Researcher), Ahmadreza Bekhradnia (Fourth Researcher), Ladan Edjlali (Third Researcher), Akram Hosseinian (Second Researcher), (First Researcher)
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