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Title New route to 1,4-oxazepane and 1,4-diazepane derivatives: synthesis from N -propargylamines
Type JournalPaper
Keywords diazepane; -propargylamine
Abstract N-Propargylamines are one of the most useful and versatile building blocks in organic synthesis that are successfully transformed into many significant N-heterocycles. Due to high atom economy and shorter synthetic routes, the synthesis of 1,4-oxazepane and 1,4-diazepane cores from N-propargylamines have undergone an explosive growth in recent years. This review gives an overview of new developments in the synthesis of the title compounds from N-propargylamines in recent years. Mechanistic aspects of the reactions are considered and discussed in detail.
Researchers Mehdi D. Esrafili (Fifth Researcher), Ahmadreza Bekhradnia (Fourth Researcher), Ladan Edjlali (Third Researcher), Akram Hosseinian (Second Researcher), (First Researcher)