چکیده
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Synthesis of CuII and PdII complexes containing 2-(2'-Hydroxyphenyl)-2-thiazoline as a
bidentate O-N donor thiazoline ligand (tzol), [Cu(tzol)2] (1), [Pd(tzol)2] (2) and their
characterization by various techniques such as IR, mass spectrometry, and elemental
analysis are reported. The structures of complexes 1 and 2 were analyzed by density
functional theory. The representative synthetic procedure involves the reaction of metal
acetate with corresponding ligand in methanol.
Two complexes [Cu(tzol)2] and [Pd(tzol)2] have shown moderate to good antibacterial
activity against Gram-positive and Gram-negative bacteria. In this study the most potent
activity was observed in Pd(II) complex against all tested strains when compared to
respective standard drugs streptomycin and ampicillin.
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