عنوان مجله
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JOURNAL OF ENVIRONMENTAL RADIOACTIVITY
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چکیده
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The hot springs in special areas in Ramsar, a northern coastal town in Iran, contain 226Ra and 222Rn.
The natural radiation effects, radiosensitivity or adaptive responses, on the inhabitants of high natural radiation
in Ramsar were studied. The single cell gel electrophoresis was used to monitor DNA damages.
Three groups of volunteers were selected, one from high natural background radiation areas as the case
group and two from normal background radiation areas as controls (control 1 and control 2). The latter
one had the similar living situation to case group while the other (control 2) had different living situation
from the other groups. Peripheral blood mononuclear cells (PMNCs) were separated and irradiated by
60Co source at five different gamma doses. It was found that the spontaneous level of DNA damage
and the induced DNA damage in all challenging doses in case group was considerably higher than control
groups ( p!0.05). On the other hand, the repair rate in those volunteers, who received less than
10.2 mSv/y was significantly more than the control groups. In the contrary, individuals who live in homes
with more than 10.2 mSv/y had incomplete repair. Additionally the plasma and urinary levels of vitamin C
were measured spectrophotometrically. Although the concentration of vitamin C of plasma was equal in
case and control 1 groups, the urinary level of vitamin C was found to be lower in the case group.
2005 Elsevier Ltd. All rights reserved.
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