عنوان مجله
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Advanced Healthcare Materials
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چکیده
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Cardiovascular disease is the leading cause of death worldwide and the most
common cause is myocardial infarction. Therefore, appropriate approaches
should be used to repair damaged heart tissue. Recently, cardiac tissue
engineering approaches have been extensively studied. Since the creation of
the nature of cardiovascular tissue engineering, many advances have been
made in cellular and scaffolding technologies. Due to the hydrated and
porous structures of the hydrogel, they are used as a support matrix to deliver
cells to the infarct tissue. In heart tissue regeneration, bioactive and
biodegradable hydrogels are required by simulating native tissue
microenvironments to support myocardial wall stress in addition to
preserving cells. Recently, the use of nanostructured hydrogels has increased
the use of nanocomposite hydrogels and has revolutionized the field of
cardiac tissue engineering. Therefore, to overcome the limitation of the use of
hydrogels due to their mechanical fragility, various nanoparticles of polymers,
metal, and carbon are used in tissue engineering and create a new
opportunity to provide hydrogels with excellent properties. Here, the types of
synthetic and natural polymer hydrogels, nanocarbon-based hydrogels, and
other nanoparticle-based materials used for cardiac tissue engineering with
emphasis on conductive nanostructured hydrogels are briefly introduced.
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