مشخصات پژوهش

صفحه نخست /Synthesis and identification ...
عنوان Synthesis and identification of Zn(BTC)‑(MOF) as a metal–organic framework for its application in the impedimetric determination of thyroxine hormone in human blood samples
نوع پژوهش مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها Metal organic frameworks · Thyroxine hormone · Electrochemically modified electrode · Cyclic voltammetry · Electrochemical impedance spectroscopy
چکیده This study discusses the determination of thyroxine hormone in blood serum samples by a novel MOF composite electrode. The used MOF was Zn(BTC)-(MOF) which was constructed from 1,3,5-benzenetricarboxylic acid ligand (BTC) and zinc ions in DMF solvent. Using cysteine as the linker, the MOF was plated on the surface of a gold electrode, formerly covered by a layer of gold nanoparticles immersed in conductive polymer polypyrrole (PPy). Different analytical methods, such as FTIR, XRD, SEM, EIS, CV, and BET, were utilized to investigate the morphology and performance of the prepared materials. The modified electrode exhibited excellent electrocatalytic ability to reduce thyroxine without interference from common coexisting substances such as different salts. The fabricated electrode has been successfully used to determine thyroxine in a linear concentration range of 10–210 nM with a detection limit of 8 nM.
پژوهشگران حسن کی پور (نفر اول)، رحمان کریمی نامی (نفر دوم)، جمال کوهدره (نفر سوم)، سمیه بابایی (نفر چهارم)، عمار مریم آبادی (نفر پنجم)، محمد طاهر رضایی (نفر ششم به بعد)، سینا شکری (نفر ششم به بعد)، صدیقه علوی نیا (نفر ششم به بعد)