|
چکیده
|
Nowadays, there is a growing tendency for the use of natural products in treatments of burn njuries, as people consider them more safe. Probiotics are living micro-organisms that may have benefits on human health. Previous studies showed that, Lactic acid bacteria, as a group of probiotics, may have beneficial effects on the skin health. Moreover, the benefits of topical use of ome strains of probiotic bacteria on the wound healing have been shown in previous researches. Because, the effects of probiotics is strictly strain dependent, in the current study, the effects of Lactobacillus acidophilus on the second degree burn wounds was studied in the rats. Material and methods: In this study the male wistar rats that were housed in a standard animal oom were used. Second degree burn wounds were induced by putting aluminum bars with the emperature of near 99 °C on the dorsum of rats for 15 seconds. The rats randomly divided nto groups of five. Negative control groups received no treatments. Positive control groups eceived ocerin as vehicle of bacteria and experimental groups received bacteria in ocerin. Then he process of healing of wounds were evaluated by measuring the wound area in the 3,7,14 days after induction of wounds. Results: Evaluation of wound area after treatments of burn wounds with the probiotic bacteria, Lactobacillus acidophilus, showed that the speed of healing process of wounds in the experimental groups were significantly faster than the control ones. In addition, evidence from tissue studies ndicates that in comparison to control groups the inflammation phase of wound healing was horter in experimental groups. Conclusion: The current study indicates that Lactobacillus acidophilus accelerates the process of wound healing. The results of present study is in agreement with the results of previous ones that indicate the positive effects of other probiotic lactic acid bacteria on the process of wound healing.
|