مشخصات پژوهش

عنوان	Interaction of Yarrowia ‎lipolytica lipase with ‎dithiocarbamate modified ‎magnetic carbon Fe3O4@ C-‎NHCS2H core-shell ‎nanoparticles
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Yarrowia lipolyticaLipase immobilizationBiocatalystFe3O4@CCore-shellDithiocarbamate
چکیده	Fe3O4@C core-shell nanoparticles were modified by (3-aminopropyl)triethoxysilane (APTES) to generate amine functionality in the surface. Then, the amine functional groups were converted to dithiocarbamate via post-modification with carbon disulfide. This nanostructure with new functional property was used to immobilize lipase (obtained from Yarrowia lipolytica U6). Biocatalytic activity of the Fe3O4@C-NHCS-LIP was studied in this project. The interaction of lipase and support though dithiocarbamate binder was examined in the hydrolysis of p-nitrophenyl laurate. In this paper, support showed a unique feature in the immobilization of lipase by maintaining the lipase activity, raising the stability of lipase, and reusability.
پژوهشگران	زهرا فتحی (نفر اول)، یوسوکه ایده (نفر ششم به بعد)، آمنه قدسی (نفر پنجم)، فرشاد درویشی هرزویلی (نفر چهارم)، صادق رستم نیا (نفر سوم)، اسماعیل دوستخواه (نفر دوم)