مشخصات پژوهش

صفحه نخست /Application of the NiO ...
عنوان Application of the NiO Catalytic Properties in Chemiluminescence Reactions for Isoniazid Determination in Luminol – Dissolved oxygen Chemiluminescence System
نوع پژوهش مقاله ارائه شده کنفرانسی
کلیدواژه‌ها Isoniazid Chemiluminescence Luminol
چکیده In this paper, a NiO hollow microspheres-luminol-dissolved oxygen chemiluminescence (CL) system was proposed for determination of isoniazid in tablet and serum samples. The NiO nanoparticles (NiO-NPs) were prepared by a simple hydrothermal method which were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), and Fourier transform infrared spectroscopy (FT-IR). The NiO-NPs have a catalytic effect on the luminol- dissolved oxygen CL system for measuring isoniazid. The effect of important parameters on determining method efficiency, such as concentration of NaOH, luminol and nanoparticles were investigated. At the optimum conditions, the calibration curve for isoniazid was obtained in the range of 8×10-7 to 1×10-4 M (R2=0.99). The detection limit of the method was obtained 2×10-7 M. In addition, the proposed method was successfully used to determination of isoniazid commercial tablets and human serum as real samples. The acceptable relative standard deviation (RSD) was obtained for the proposed CL method (2.63%, n=10).
پژوهشگران مهدیه حسن پور (نفر اول)، مرتضی ایرانی فام (نفر دوم)، عبدالحسین ناصری (نفر سوم)، حیدر الف ج اللواتی (نفر چهارم)