مشخصات پژوهش

صفحه نخست /Efficient conversion of ...
عنوان Efficient conversion of bio-waste lignin into high-value fluorescent nitrogen-modified carbon quantum dots for live-cell imaging
نوع پژوهش مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها Keywords: Bio-waste lignin Microwave conversion Carbon quantum dot Surface modification Biological imaging
چکیده Sustainable and green natural lignin raw materials are considered as reliable precursors for large-scale production of carbon quantum dots (CQDs). However, extracting CQDs with ultra-low cytotoxicity and favorable fluorescence properties from lignin remains a challenge. Herein, the bio-waste lignin was converted into crude CQDs by an eco-friendly and rapid microwave pyrolysis approach in just 15 min. The as-obtained CQDs modified with nitrogen-atoms (N-CQDs) display a representative graphite-like structure, strong hydrophilicity, tiny particle size of 6.9 nm, and bright green fluorescence with a quantum yield of approximately 22.2% and fluorescence lifetime of 4.29 ns. Moreover, the N-CQDs exhibit high fluorescence stability under the conditions of a range of pH (5–11), continuous UV irradiation (~2 h), and NaCl presence with concentrations of 0–1.2 mol/L. More importantly, the N-CQDs show negligible cytotoxicity. Even at the higher N-CQD concentration (300 μg/ mL), A549 cells still maintain over 90% activity. The N-CQDs could be utilized for fluorescence imaging in living cells based on the above favorable characteristics. The present work paves the way for the value-added utilization of bio-waste lignin and the production of safe cell imaging agents.
پژوهشگران شوانی وانگ (نفر ششم به بعد)، شین شین لیان (نفر پنجم)، محسن پادروند (نفر چهارم)، تینگ گائو (نفر سوم)، عبدلکادر لبیدیا (نفر دوم)، هایتاو رن (نفر اول)